83,582 research outputs found

    Subject-specific finite element modelling of the human hand complex : muscle-driven simulations and experimental validation

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    This paper aims to develop and validate a subject-specific framework for modelling the human hand. This was achieved by combining medical image-based finite element modelling, individualized muscle force and kinematic measurements. Firstly, a subject-specific human hand finite element (FE) model was developed. The geometries of the phalanges, carpal bones, wrist bones, ligaments, tendons, subcutaneous tissue and skin were all included. The material properties were derived from in-vivo and in-vitro experiment results available in the literature. The boundary and loading conditions were defined based on the kinematic data and muscle forces of a specific subject captured from the in-vivo grasping tests. The predicted contact pressure and contact area were in good agreement with the in-vivo test results of the same subject, with the relative errors for the contact pressures all being below 20%. Finally, sensitivity analysis was performed to investigate the effects of important modelling parameters on the predictions. The results showed that contact pressure and area were sensitive to the material properties and muscle forces. This FE human hand model can be used to make a detailed and quantitative evaluation into biomechanical and neurophysiological aspects of human hand contact during daily perception and manipulation. The findings can be applied to the design of the bionic hands or neuro-prosthetics in the future

    Prizes and Lemons: Procurement of Innovation under Imperfect Commitment

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    The literature on R&D contests implicitly assumes that contestants submit their innovation regardless of its value. This ignores a potential adverse selection problem. The present paper analyzes the procurement of innovations when the procurer cannot commit to never bargain with innovators who bypass the contest. We compare ?xed-prize tournaments with and without entry fees, and optimal scoring auctions with and without minimum score requirement. Our main result is that the optimal ?xed-prize tournament is more pro?table than the optimal auction since preventing bypass is more costly in the optimal auction

    A Practical Blended Analysis for Dynamic Features in JavaScript

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    The JavaScript Blended Analysis Framework is designed to perform a general-purpose, practical combined static/dynamic analysis of JavaScript programs, while handling dynamic features such as run-time generated code and variadic func- tions. The idea of blended analysis is to focus static anal- ysis on a dynamic calling structure collected at runtime in a lightweight manner, and to rene the static analysis us- ing additional dynamic information. We perform blended points-to analysis of JavaScript with our framework and compare results with those computed by a pure static points- to analysis. Using JavaScript codes from actual webpages as benchmarks, we show that optimized blended analysis for JavaScript obtains good coverage (86.6% on average per website) of the pure static analysis solution and nds ad- ditional points-to pairs (7.0% on average per website) con- tributed by dynamically generated/loaded code
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